教育背景
2007.09~2012.07 中国科学院,理化技术研究所硕博连读,获博士学位
2003.09~2007.07 北京师范大学,化学学院,获学士学位
工作经历
2019.08~至今 内蒙古大学,6165cc金沙总站检测中心, 副教授
2014.07~2019.08 赣南师范大学,6165cc金沙总站检测中心, 副教授
2012.07~2014.07 中国科学院理化技术研究所,助理研究员
荣誉与奖励
2020年,入选内蒙古自治区第十批“草原英才”
2018年,入选江西省科技创新杰出青年人才
研究领域
课题组网站:https://www.x-mol.com/groups/Wang_Jianguo
1. 光电功能材料
2. 疾病诊断与治疗
3. 化学/生物传感器。
教学
主讲大学化学、分析化学实验等
研究项目
1. 国家自然科学基金地区科学基金,触发式自降解分子与光敏剂分子的复合体系用于靶向光动力抗癌的活性研究,2017.01- 2020.12,主持。
2. 国家自然科学基金青年基金项目,利用上转换纳米颗粒构筑近红外激发的钌(II)多吡啶类光活化化疗药物,2014.01-2016.12,主持。
3. 第十批“草原英才”,2020.01-2022.12,主持。
4. 内蒙古大学科研人才引进“学术骨干”,2020-2022,主持。
5. 内蒙古自治区自然科学基金面上项目,聚集诱导发光特性荧光分子的设计合成及致病菌鉴别、光动力抗菌研究,2020.01-2022.12,主持。
6. 江西省自然科学杰出青年基金项目,利用聚集诱导发光现象开发可激活turn-on型癌症早期荧光诊断新方法,2018.01-2020.12,主持。
7. 江西省自然科学基金青年基金项目,利用四苯乙烯类AIE分子与葫芦脲[7]形成的超分子结构构筑选择性识别精胺的探针,2017.01-2018.12,主持。
8. 江西省自然科学基金青年基金项目,利用上转换纳米颗粒构筑近红外激发的光控释放一氧化碳的药物,2015.01-2016.06,主持。
9. 江西省教育厅科技项目,利用四苯乙烯的聚集荧光检测尿液中的脂多糖,2016.1-2017.06,主持。
10. 赣州市科技创新人才计划项目,2019.01-2021.12,主持。
11. 中国科学院光化学转换与功能材料重点实验室开放课题,利用上转换纳米颗粒构筑近红外激发的光控释放一氧化碳的药物,2015.06- 2016.06,主持。
代表性成果
发表SCI期刊学术论文37篇,其中以第一或通讯作者在Anal. Chem., Adv. Opt. Mater., Chem. Commun.等国际著名期刊上发表论文25篇,申请发明专利10项,已授权发明专利8项;参与编写《Handbook of Aggregation-Induced Emission》(Wiley Press)英文专著第11章。在国内外高水平学术会议上做邀请/口头报告10余次。
论文:(近五年部分代表性论文)
1. Guoyu Jiang, Chunbin Li, Qingfang Lai, Xiang Liu, Qingqing Chen, Pengfei Zhang, Jianguo Wang*, Ben Zhong Tang*, An Easily Available Ratiometric AIE Probe for Peroxynitrite in vitro and in vivo Imaging, Sens. Actuators B: Chem., 2021, 329, 129223. (SCI一区)
2. Chunbin Li, Guoyu Jiang, Xiang Liu, Qingfang Lai, Miaomiao Kang, Dong Wang, Pengfei Zhang, Jianguo Wang*, Ben Zhong Tang*, An Easily Available Ratiometric AIE Probe for Nitroxyl Visualization in vitro and in vivo Imaging, Mater. Chem. Front., 2021, 5, 1817-1823. (HOT Article) (SCI一区)
3. Guoyu Jiang, Chunbin Li, Xiang Liu, Qingqing Chen, Xiaokang Li, Xinggui Gu, Qingfang Lai, Jianguo Wang*, Lipid droplet‐targetable fluorescence guided photodynamic therapy of cancer cells with an activatable AIE‐active fluorescent probe for hydrogen peroxide, Adv. Opt. Mater., 2020, 8, 2001119. (SCI一区)
4. Jianguo Wang, Wenping Zhu, Chunbin Li, Pengfei Zhang, Guoyu Jiang*, Guangle Niu*, Ben Zhong Tang*, Mitochondria-targeting NIR fluorescent probe for rapid, highly sensitive and selective visualization of nitroxyl in live cells, tissues and mice, Sci. China Chem., 2020, 63, 282-289. (SCI一区)
5. Qiang Wang, Chunbin Li, Qingqing Chen, Pengfei Zhang, Dong Wang, Miaomiao Kang, Guoyu Jiang*, Jianguo Wang*, Lysosome-targeting red-emitting aggregation-induced emission probe with large stokes shift for light-up in situ visualization of β‑N‑acetylhexosaminidase. Anal. Chem., 2019, 91, 12611-12614. (SCI一区)
6. Jianguo Wang, Chunbin Li, Qingqing Chen, Hongfeng Li, Lihua Zhou, Xing Jiang, Mengxue Shi, Pengfei Zhang*, Guoyu Jiang*, Ben Zhong Tang*, An easily available ratiometric reaction-based AIE probe for carbon monoxide light-up imaging, Anal. Chem., 2019, 91, 9388-9392. (SCI一区)
7. Jianguo Wang, Wenping Zhu, Guangle Niu, Guoyu Jiang*, Qingqing Chen, Pei Gao, Yongdong Li, Guanxin Zhang, Xiaolin Fan, Ben Zhong Tang*, Selectively light-up hydrogen peroxide in hypoxic cancer cells with a novel fluorescent probe, Chem. Commun., 2018, 54, 13957-13960. (SCI一区)
8. Jianguo Wang, Lik-Kuen Ma, Jiachen Huang, Ming Chen, Zitong Liu, Guoyu Jiang*, He Yan*, Side-chain effect of perylene diimide tetramer-based non-fullerene acceptors for improving the performance of organic solar cells, Mater. Chem. Front., 2018, 2, 2104-2108. (2018年第三季度最受欢迎文章)
9. Guoyu Jiang, Wenping Zhu, Qingqing Chen, Xinbo Li, Guanxin Zhang, Yongdong Li*, Xiaolin Fan, Jianguo Wang*, Selective fluorescent probes for spermine and 1-adamantanamine based on the supramolecular structure formed between AIE-active molecule and cucurbit[n]urils. Sens. Actuators B: Chem., 2018, 261, 602-607. (SCI一区)
10. Jianguo Wang, Qingqing Chen, Na Tian, Wenping Zhu, Hang Zou, Xiaokang Li, Xiaolin Fan, Guoyu Jiang*, Ben Zhong Tang*, A fast responsive, highly selective and light-up fluorescent probe for two-photon imaging of carboxylesterase in living cells. J. Mater. Chem. B., 2018, 6, 1595-1599. (SCI二区)
11. Guoyu Jiang, Guanjie Zeng, Wenping Zhu, Yongdong Li, Xiaobiao Dong, Guanxin Zhang, Xiaolin Fan, Jianguo Wang*, Yongquan Wu*, Ben Zhong Tang*, A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative, Chem. Commun., 2017, 53, 4505-4508. (SCI一区)
12. Guoyu Jiang, Xiang Liu, Qingqing Chen, Guanjie Zeng, Yongquan Wu, Xiaobiao Dong, Guanxin Zhang, Yongdong Li*, Xiaolin Fan, Jianguo Wang*, A new tetraphenylethylene based AIE probe for light-up and discriminatory detection of Cys over Hcy and GSH, Sens. Actuators B: Chem., 2017, 252, 712–716. (SCI一区)
13. Guoyu Jiang, Jianguo Wang*, Yang Yang, Guanxin Zhang*, Yaling Liu, He Lin, Guilan Zhang, Yongdong Li*, Xiaolin Fan, Fluorescent turn-on sensing of bacterial lipopolysaccharide in artificial urine sample with sensitivity down to nanomolar by tetraphenylethylene based aggregation induced emission molecule, Biosens. Bioelectron., 2016, 85, 62-67. (SCI一区)
专利:
1. 王建国,姜国玉,吴勇权,范小林,李勋,具有聚集诱导荧光增强特性的氟离子传感器的合成及应用,专利号:ZL 201610323833.9。
2. 王建国,姜国玉,朱温平,吴勇权,范小林,一种基于聚集诱导发光原理用于选择性检测半胱氨酸的荧光试剂的合成及应用,专利号:ZL 201710153023.X。
3. 王建国,姜国玉,吴勇权,范小林,一种基于聚集诱导荧光增强特性用于选择性识别ATP的荧光探针、合成方法及其应用,专利号:ZL 201710143038.8。
4. 王建国,姜国玉,陈青青,李勋,范小林,一种羧酸酯酶荧光探针及其制备方法和应用,专利号:ZL 201810129535.7。
5. 王建国,姜国玉,吴勇权,范小林,具有聚集诱导荧光增强特性的β-半乳糖苷酶传感器的合成及应用,专利号:ZL 201610538734.4。
6. 王建国,姜国玉,王强,一种氨基己糖酶荧光探针及其制备方法及应用,专利号:201910541339.5。
7. 王建国,姜国玉,刘祥,一种兼具双氧水检测和光动力杀伤癌细胞活性的荧光探针及其制备方法和应用,专利号:201910997394.5。
8. 王建国,姜国玉,朱温平,一种具有双光子和近红外发光特性的亚硝酰氢荧光探针及其制备方法和应用,专利号:201910157417.1。
9. 王建国,姜国玉,李纯斌,一种具有聚集诱导发光特性的比率型一氧化碳荧光探针的设计合成及应用,专利号:ZL201910299561.9。
10. 王建国,姜国玉,王强,一种9,10-二(N-(2,3-二羟丙基)丙酰胺基)蒽的制备方法,专利号:201910127803.6。